
La Quinta Inn & Suites Sioux Falls
Best for families and short-stay travelers who want a central location near Empire Mall, a hot breakfast, and an indoor pool/hot tub.
Prices in other currencies are estimates. You’re charged in USD.
La Quinta Inn & Suites Sioux Falls is a 3-star, family-friendly hotel in the mall district with an indoor heated pool, basic meeting space, and free hot breakfast. Home2 Suites By Hilton Sioux Falls/Sanford Medical Center is a 3-star extended-stay, all-suite Hilton property near Sanford USD Medical Center; read this if you want a suite-style stay with in-room kitchens and longer-stay comforts.
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Best for families and short-stay travelers who want a central location near Empire Mall, a hot breakfast, and an indoor pool/hot tub.

Best for longer stays, travelers who prefer suite layouts with kitchens, and guests needing easy access to Sanford USD Medical Center or nearby colleges.
When La Quinta wins: Choose La Quinta Inn & Suites Sioux Falls if you want a straightforward, family-friendly hotel in the Mall District with a full hot Bright Side Breakfast, a large fitness center, an indoor heated pool and hot tub, and a compact meeting room for small events.
When Home2 wins: Pick Home2 Suites if you need a studio or 1‑bedroom suite with a kitchenette (fridge and microwave), prefer Hilton’s extended-stay design, or are staying multiple nights and want more in-room living space plus 24-hour fitness and a conference room option.
Bottom line: Both are practical 3-star Sioux Falls choices. La Quinta is the more traditional, family- and event-ready option in the retail district; Home2 Suites targets extended-stay guests and travelers wanting suite-style rooms and in-room kitchens near medical and university destinations.
| Category | La Quinta Inn & Suites Sioux Falls | Home2 Suites |
|---|---|---|
| Overall vibe | Family-oriented, practical hotel in the mall district | Extended-stay, suite-style Hilton aimed at longer visits |
| Location context | Just off I‑29 in the Empire Mall / Mall District | In University Heights near Sanford USD Medical Center |
| Size | 89 rooms across 4 floors | 80 guestrooms |
| Stars & rating | 3 stars (brand standard); guest-rating not provided here | 3 stars, user rating 9.4 |
| Pool | Indoor heated pool plus indoor hot tub/whirlpool | Indoor pool (wheelchair-accessible) — no staffed spa listed |
| Rooms | Standard rooms and Deluxe Suite; fridges, microwaves, coffee maker in every room | Studio and 1‑bedroom suites with kitchens (refrigerator, microwave); many accessible room types |
| Breakfast | Free hot Bright Side Breakfast (hot & cold items) | Complimentary on-the-go breakfast served daily 6–9 AM |
| Meeting & events | One meeting room, 990 sq ft (capacity ~60) | Conference/meeting space about 950 sq ft |
| Fitness | Large, fully equipped fitness center (commercial-grade equipment) | 24-hour fitness facilities; wheelchair-accessible fitness center |
| Pets & accessibility | Pets allowed (fee varies by source); service animals exempt; accessible rooms available | Pet policy: USD 50 per stay (supplier listing); many accessible room types and accessible parking/pathways |
La Quinta sits just off Interstate 29 near the Empire Mall retail district, good for shopping and mall-area restaurants.
A practical choice if you want quick access to shopping and mall-district dining.
Home2 Suites is in University Heights close to Sanford USD Medical Center and several colleges.
Better suited to guests needing proximity to medical centers or campus destinations.
La Quinta offers standard rooms and a Deluxe Suite; all rooms include a refrigerator, microwave, and coffee maker.
Good for families and guests who want simple, reliable rooms with in-room fridges and microwaves.
Home2 Suites is an extended-stay Hilton with studio and 1-bedroom suites that include kitchens.
Choose Home2 for more living space and kitchen facilities for longer stays or self-catering.
La Quinta provides the Bright Side Breakfast free to guests each morning but has no on-site restaurant.
Breakfast is included; for other meals you'll rely on surrounding restaurants.
Home2 Suites offers a complimentary on-the-go breakfast and in-room kitchenettes for self-catering.
Home2 is convenient for self-catering and quick grab-and-go breakfasts.
La Quinta has an indoor heated pool and an indoor hot tub alongside a well-regarded fitness center.
Strong option if an indoor pool and a substantial fitness room matter for your stay.
Home2 Suites provides an indoor pool and a 24-hour fitness center; the property highlights accessibility features for the pool.
Good for guests who want a suite and basic pool/fitness facilities, with added outdoor grill space.
La Quinta covers basic business and wellness needs with a business center, meeting room, and laundry facilities.
A sensible choice for small meetings and events with family-friendly support services.
Home2 Suites lists business-friendly and accessible facilities, plus a similar-sized conference space.
Home2 offers meeting space and strong accessibility features alongside extended-stay conveniences.

La Quinta — walkable/very close to Empire Mall and many mall-area restaurants.

Home2 Suites — suites with kitchens and larger studio/1‑bedroom layouts make longer visits easier.

La Quinta — kids-stay-free policy, family-friendly room types, and an indoor hot tub.

Home2 Suites — location steps from Sanford USD Medical Center and several university sites.
La Quinta — it’s in the Mall District, offers a hot complimentary breakfast, and has an indoor heated pool and hot tub.
Home2 Suites — suites include kitchens (fridge and microwave) and are designed for extended stays.
Neither property lists a full-service restaurant or a staffed spa; La Quinta offers a free hot Bright Side Breakfast and Home2 offers an on-the-go breakfast and in-room kitchens.
Both properties list accessible rooms and features. La Quinta allows pets (fees and limits vary by source) and Home2 Suites lists a pet fee (USD 50 per stay per supplier listing); confirm policies with each hotel before arrival.
Explore how La Quinta Inn & Suites Sioux Falls stacks up against other hotels nearby:
vs. sites like Expedia, Hotels.com and other OTAs ·